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科研成果

 

 

2020-2023年科研成果
2023-06-13 15:58  

近三年发表科研论文近50篇,其中中科院一区Top期刊发表论文6篇。

序号

作者姓名

文章名称

期刊类别

期刊名称

年、卷期、页码

中科院分区

1

赵星

NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering cisplatin and reactivating NK cell functions.

SCI

Front Immunol.

2023 Jan 19;13:1087689

Q1

2

范安然

APP mediates tau uptake and its overexpression leads to the exacerbated tau pathology

SCI

Cell Mol Life Sci.

2023 Apr 18;80(5):123.

Q1

3

范安然

Tet2-mediated DNA demethylation regulates the proliferation and apoptosis of human leukemia K562 cells

SCI

Cell MolBiol (Noisy-le-grand)

2023 Mar 31;69(3):23-27.

Q4

4

赵友波

Recent Progress in the Therapeutic Modulation of Lactate for Cancer Treatment

SCI

Adv. Therap.

2022, 2200254

Q4

5

张荣红

Design, synthesis, and in vitro protective effect evaluation ofα-carboline derivatives against H2O2-induced cardiomyocyte injury

SCI

European Journal of Medicinal Chemistry

2022 Aug 5;238:114469

Q1

6

张荣红

Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.

SCI

Molecules.

2022 Jun 23;27(13):4040.

Q3

7

许键炜

hUC-MSCs: evaluation of acute and long-term routine toxicity testing in mice and rats

SCI

Cytotechnology.

2022 Feb;74(1):17-29.

Q4

8

赵星

Recombinant human endostatin combined with radiotherapy promotes cardiomyocyte apoptosis in rats via TGFβ1/Smads/CTGF signaling pathway.

SCI

BMC CardiovascDisord.

2022 Mar 12;22(1):97.

Q4

9

赵星

mRNA vaccines in the prevention and treatment of diseases.

SCI

MedComm (2020).

2022 Aug 25;3(3):e167.

Q3

10

王静娴

Integrative omics analysis identifies biomarkers of idiopathic pulmonary fibrosis.

SCI

Cell Mol Life Sci.

2022 Jan 11;79(1):66.

Q2

11

叶川

(兼职PI)

Biomechanical analysis of the drilling parameters for early osteonecrosis of the femoral head.

SCI

Comput Methods Programs Biomed.

2022 Jun;219:106737.

Q2

12

叶川

(兼职PI)

Precise Patellar Tendon Insertion Protection and Osteotomy Surface Advantage of Transtibial Tuberosity-High Tibial Osteotomy.

SCI

Orthop Surg.

2022 Nov 23.

Q3

13

叶川

(兼职PI)

Improve biomechanical stability using intramedullary nails with femoral neck protection in femoral shaft fractures. Comput

SCI

Methods Programs Biomed.

2022 Oct;225:107078.

Q2

14

叶川

(兼职PI)

In situ cell electrospun using a portable handheld electrospinning apparatus for the repair of wound healing in rats.

SCI

Int Wound J.

2022 Nov;19(7):1693-1704.

Q3

15

叶川

(兼职PI)

Impact of Femoral Neck Cortical Bone Defect Induced by Core Decompression on Postoperative Stability: A Finite Element Analysis.

SCI

Biomed Res Int.

2022 May

Q4

16

叶川

(兼职PI)

Clinical efficacy and feasibility of laser correction technology with an ordinary laser pen and surgical instrument box in open-wedge high tibial osteotomy.

SCI

BMC MusculoskeletDisord.

2022 Nov 26;23(1):1019.

Q4

17

赵星

Reovirus enhances cytotoxicity of natural killer cells against colorectal cancer via TLR3 pathway

SCI

J Transl Med

2021 May 1;19(1):185.

Q2

19

赵星

Oncolyticreovirus induces ovarian cancer cell apoptosis in a TLR3-dependent manner

SCI

Virus Research

2021 Aug;301:198440.

Q3

20

赵星

Immunoregulatory therapy strategies that target cytokine storms in patients with COVID-19

SCI

ExpTher Med

2021 Apr;21(4):319.

Q4

21

赵星

Mesenchymal stem cell carriers enhance antitumor efficacy of oncolyticvirotherapy

SCI

OncolLett

2021 Apr;21(4):238.

Q4

22

范安然

Mouse fetal liver cell-derived exosomes inhibit LPS-induced inflammation in microglia

SCI

ALL LIFE

2021,14(1):709-718

Q4

23

苏敏

BTN2A2 protein negatively regulates T cells to ameliorate collagen-induced arthritis in mice

SCI

Scientific Reports

2021 Sep 29;11(1):19375.

Q3

24

张鹏

Cytosine base modifications regulate DNA duplex stability and metabolism

SCI

Nucleic Acids Res

2021 Dec 16;49(22):12870-12894.

Q1

25

赵星

Bone marrow-derived mesenchymal stem/stromal cells in patients with acute myeloid leukemia reveal transcriptome alterations and deficiency in cellular vitality.

SCI

Stem cell research & therapy

2021 Jun 26;12(1):365.

Q2

26

叶川

(兼职PI)

Clean version: Electrospun fibrinogen scaffolds from discarded blood for wound healing

SCI

J Biomed Mater Res B ApplBiomater

2021 Aug;109(8):1145-1155.

Q3

27

叶川

(兼职PI)

Electrospun egg white/polyvinyl alcohol fiber dressing to accelerate

wound healing

SCI

Journal of Polymer Research

2021,28: 67

Q3

28

许键炜

Application in Gene Editing in Ovarian Cancer Therapy

SCI

Cancer Invest

2021 Nov 11;1-13.

Q4

29

张荣红

Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities

SCI

Eur J Med Chem

2021 Oct 15;222:113573

Q1

30

张荣红

Synthesis strategies forα-,β-,γ- andδ-carbolines

SCI

Asian Journal Of Organic Chemistry

2021.DOI:10.1002/ajoc.202000690.

Q3

31

苏敏

Changes of immune parameters of T lymphocytes and macrophages in EAE

mice after BM-MSCs transplantation

SCI

Immunology Letters

2020 Sep;225:66-73.

Q3

32

苏敏

ERMAP is a B7 family-related molecule that negatively

regulates T cell and macrophage responses

SCI

Cell MolImmunol

2020 Jul 3.

Q1

33

赵星

The influence of oncolyticreovirus on the biological activities of umbilical cord-derived mesenchymal stem cells

SCI

Eur Rev Med PharmacolSci

2020,24:10839-10849

Q3

34

张荣红

Discovery of tetrandrine derivatives as tumor migration, invasion and angiogenesis inhibitors

SCI

Bioorganic Chemistry

101 (2020) 104025

Q2

35

王静娴

Serum SP-A and KL-6 levels can predict the improvement and deterioration of patients with interstitial pneumonia with autoimmune features

SCI

BMC Pulmonary medicine

(2020) 20:315

Q3

36

许键炜

Deep thought of COVID-19 based on Diamond Princess's quarantine and home quarantine

SCI

European Review for Medical and Pharmacological Sciences

2020,24 : 4017-4019.

Q3

37

许键炜

Erythropoietin-Mmodifiedmesenchymal stem cells enhance anti-fibrosis efficacy in mouse liver fibrosis model

SCI

Tissue Engineering and Regenerative Medicine

2020,17:683-693.

Q4

38

叶川

(兼职PI)

Osteoblastic differentiation of stem cells induced by graphene oxide-hydroxyapatite-alginate hydrogel composites and construction of tissue-engineered bone

SCI

J Mater Sci Mater Med

2020 Nov 28;31(12):125

Q3

39

叶川

(兼职PI)

Biofabrication of valentine-shaped heart with a composite hydrogel and sacrificial material

SCI

Mater SciEng C Mater BiolAppl

2020 Mar;108:110205

Q2

40

叶川

(兼职PI)

Correlation between the efficacy of stem cell therapy for osteonecrosis of the femoral head and cell viability.

SCI

BMC MusculoskeletDisord

21, 55 (2020).

Q4

41

叶川

(兼职PI)

Fabrication of multilayered electrospun poly(lactic-co-glycolic acid)/polyvinyl pyrrolidone + poly(ethylene oxide) scaffolds and biocompatibility evaluation

SCI

J Biomed Mater Res A.

2020 Dec 2.

Q3

42

叶川

(兼职PI)

Intra-Articular Platelet-Rich Plasma Combined With Hyaluronic Acid Injection for Knee Osteoarthritis Is Superior to Platelet-Rich Plasma or Hyaluronic Acid Alone in Inhibiting Inflammation and Improving Pain and Function

SCI

Arthroscopy.

2021 Mar;37(3):903-915.


43

张鹏

基于高分辨率熔解曲线技术的CRISPR/Cas9介导的细胞基因突变快速检测研究

梯队期刊

生物技术通报

2022, 38(9):12-18


44

许键炜

miR-26b调控Wnt/β-catenin信号通路促进成肝样分化MSCs迁移研究

北大核心

安徽医科大学学报

2020,55(12):1850-1857


45

许键炜

苗药加九留对骨折愈合的修复作用

一般期刊

亚太传统医药

2020,16(7):28-30.


46

许键炜

重点实验室在创新型医学本科人才培养中的实践

一般期刊

基础医学教育

2020,22(3):203-206.


47

许键炜

吉祥草水提物对小鼠慢性阻塞性肺疾病的作用和机制

一般期刊

贵州医科大学学报

2020,12:1412-1416


48

许键炜

溃疡性结肠炎并结节性红斑及自身免疫性甲状腺炎1例报告并文献复习

一般期刊

临床医药文献电子杂志

2020,80


49

许键炜

间充质干细胞治疗神经系统疾病的研究进展

一般期刊

癫痫与神经电生理学杂志

2020,4


2.科研奖励

序号

奖励名称

授予单位

获奖人

授予年份

1

贵州省科学技术奖自然科学二等奖

贵州省科学技术厅

舒莉萍

2020

2

贵州省医学科技奖二等奖

贵州省医学会

苏敏

2021

3

贵州省医学科技奖二等奖

贵州省医学会

赵星

2018

3.发明专利

序号

专利名称

专利类别

完成人

批准年份

1

一种在红系细胞中特异表达人β珠蛋白的重组序列及其应用

发明专利

张鹏,杨红兰,何志旭,刘含,周艳华,范安然

授权(2021)

2

一种用于驱动基因在人红细胞系统中特异表达的启动子及应用

发明专利

张鹏,刘含,何志旭,范安然,周艳华,杨红兰

授权(2021)

3

带g6pd1303‑1497位点缺失的转基因斑马鱼模型及构建方法

发明专利

舒莉萍,何志旭,吴西军,周艳华,夏海雄,宋锦,庹媛媛,尚鲁俊

授权(2019.10)

4

一种实验室内课题组科研管理系统

国际发明专利

张鹏,赵国静,周艳华,范安然,盛长红,曾柱,郭兵,何志旭

申请(2022)

5

一种实验室规范化系统

国际发明专利

张鹏,赵国静,范安然,周艳华,黄文竹,曾柱,郭兵,何志旭

申请(2022)

6

靶向治疗习惯性流产和免疫性不孕的细胞及其制备方法

发明专利

许键炜,秦臻,何志旭,周谊霞,杨小燕,周艳华,熊英,王岚,张丽娟,汪显耀,匡梦岚,孙小霞

申请(2020)

7

含脐带间充质干细胞培养液提取物的生物养颜修护面膜精华、面膜及其制备方法

发明专利

许键炜,吕宇,何志旭,周谊霞,秦臻,王品权,舒莉萍,熊英,刘忠山,吴西军,张丽娟,汪显耀

申请(2019)

8

一种液氮罐液量报警装置

实用新型

周艳华,张鹏,范安然,苏敏,许键炜,郭兵,曾柱,何志旭

授权(2021.11)

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