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陈虹锦 副教授

发布日期:2025-10-02    点击:

个人简历

陈虹锦副教授博士后硕、博士青年导师

电子邮件:chenhongjin@gmc.edu.cn

贵州医科大学-心血管疾病基础与临床研究重点实验室副主任,《Frontiers in Pharmacology》客座编辑,《Cancer Insight》杂志编委。

教育经历

2018.09-2021.06,南京医科大学-新加坡国立癌症中心,病理学与病理生理学,博士

2014.09-2017.06,温州医科大学,中药学,硕士

2010.09-2014.06,广州中医药大学,中药资源与开发,学士

工作经历

2023.01-至今,贵州医科大学,组织工程与干细胞转化实验中心,副教授

2021.09-2022.12,贵州医科大学,转化医学研究中心,讲师

2017.08-2018.09,温州医科大学,化学生物学研究中心,研究助理

研究方向

炎症代谢性疾病。

代表性项目成果

  1. 国基自然科学基金,地区基金,82260567,FGFBP1诱导慢性炎症促进胰腺癌恶性表型的机制研究,2023.1-2026.12,34.0万元,在研,主持。

  2. 贵州省基础研究计划(自然科学项目),黔科合基础-ZK[2023]一般321,异甘草素靶向SIRT1缓解糖尿病中慢性炎症致心肌损伤的作用机制研究,2023.1-2025.12,10.00万元,在研,主持。

  3. 贵州医科大学优秀青年拔尖人才项目,2023.7-2028.6,100万元,在研,主持。

    教学情况

    主讲本科药理学课程。

    论文、专著及专利等

    在学术刊物上发表科研论文30余篇。代表作:

    第一作者

    1. Hongjin Chen, et al. Centromere protein F is identified as a novel therapeutic target by genomics profile and contributing to the progression of pancreatic cancer, Genomics. 2020 Nov 6;S0888-7543(20)32003-6. doi: 10.1016/j.ygeno.2020.10.039.

    2. Hongjin Chen, et al. Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury. Phytomedicine, 2019, 63:152997.

    3. Hong-Jin Chen, et al. Understanding the inflammation-cancer transformation in the development of primary liver cancer, Hepatoma Research, 2018;4:29. DOI: 10.20517/2394-5079.2018.18.

    4. Hongjin Chen, et al. Inhibition of high glucose-induced inflammation and fibrosis by a novel curcumin derivative prevents renal and heart injury in diabetic mice. Toxicology Letters, 2017, 278:48-58.

    5:Hongjin Chen, et al. Overexpression of RhoV promotes the progression and EGFR-TKI resistance of lung adenocarcinoma, Frontiers in Oncology, 2021 Mar 9:11:619013.

    6:Hongjin Chen, et al. Centromere protein F promotes progression of hepatocellular carcinoma through ERK and cell cycle-associated pathways, Cancer Gene Therapy, 2022 Jul;29(7):1033-1042.

    7:Hongjin Chen, et al. Curcumin Derivative C66 Suppresses Pancreatic Cancer Progression through the Inhibition of JNK-Mediated Inflammation, Molecules, 2022 May 11;27(10):3076.

    8:Hongjin Chen, et al. Acute or chronic inflammation role in gastrointestinal oncology, World J Gastrointest Oncol. 2022 Aug 15;14(8):1600-1603.

    9:Hongjin Chen, et al. Multifunctional roles of inflammation and its causative factors in primary liver cancer: A literature review. World J Hepatol .2023 Dec 27;15(12):1258-1271.

    10: Hongjin Chen, et al. Effects of vitamin family members on insulin resistance and diabetes complications. World J Diabetes. 2024 Mar 15;15(3):568-571.

    通讯作者

    1. Yi Zhang# , Hui Liu# , Wenjing Jia# , Jiayu Qi, Wentao Zhang, Wenxin Zhang, Guang Liang, Yali Zhang, Hongjin Chen*. Myeloid differentiation protein 2 mediates angiotensin II induced liver inflammation and fibrosis in mice. Molecules, 2020, 25(1), 25.

    2. Jue Bai#, Si-Yuan Yang#, Shao-Mei Yu, Ying Cao, Xuan-Yi Hu, Xiong Chen, Ying-Nan Song*, Hong-Jin Chen*, IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance, Frontier in Pharmacology,2025 Apr 29:16:1544869.

    3.miR-92a-1-5p targeting MEF2A induced Insulin Resistance in Myocardial Ischemia/Reperfusion Injury,Biochem Biophys Res Commun,2025 Jul 1:768:151938.

    4. Isoliquiritigenin inhibited complete Freund's adjuvant-induced chronic inflammatory pain via the CCL7/CCR2/ERK pathway in dorsal root ganglia neurons of mice,International Immunopharmacology,Volume 170, 1 February 2026, 116059

    并列第一作者(6篇)

    1. Xiaozhong Huang, et al, Cell Death Dis. 2020 Dec 7;11(12):1040. doi: 10.1038/s41419-020-03260-9.(SCI,二区,IF=6.3,共一/自然序列:第三作者)

    2. Yali Zhang, et al, BBA - Molecular Basis of Disease, 2020 Jan 14;1866(5):165683.(SCI,二区,IF=4.8,共一/自然序列:第二作者)

    3. Chunyong Ding, et al, Chemical Science, 2019, 10:4667-4672.(SCI,一区,IF=9.34,共一/自然序列:第二作者)

    4. Lingfeng Chen, et al. European Journal of Medicinal Chemistry, 2019: 161, 22-38.(SCI,一区,IF=5.573,共一/自然序列:第二作者)5. Dandan Liang, et al. BBA - Molecular Basis of Disease, 2018, 1864(1): 133-142.(SCI,二区,IF=4.8,共一/自然序列:第二作者)6. Lingfeng Chen, et al. Eur. J Med. Chem, 2017, 143: 361-375.(SCI,一区,IF=5.573,共一/自然序列:第三作者)