
个人简历
陈虹锦副教授博士后博士硕、博士青年导师
电子邮件:chenhongjin@gmc.edu.cn
贵州医科大学-心血管疾病基础与临床研究重点实验室副主任,《Frontiers in Pharmacology》客座编辑,《Cancer Insight》杂志编委。
教育经历
2018.09-2021.06,南京医科大学-新加坡国立癌症中心,病理学与病理生理学,博士
2014.09-2017.06,温州医科大学,中药学,硕士
2010.09-2014.06,广州中医药大学,中药资源与开发,学士
工作经历
2023.01-至今,贵州医科大学,组织工程与干细胞转化实验中心,副教授
2021.09-2022.12,贵州医科大学,转化医学研究中心,讲师
2017.08-2018.09,温州医科大学,化学生物学研究中心,研究助理
研究方向
炎症代谢性疾病。
代表性项目成果
[1] 国基自然科学基金,地区基金,82260567,FGFBP1诱导慢性炎症促进胰腺癌恶性表型的机制研究,2023.1-2026.12,34.0万元,在研,主持。
[2] 贵州省基础研究计划(自然科学项目),黔科合基础-ZK[2023]一般321,异甘草素靶向SIRT1缓解糖尿病中慢性炎症致心肌损伤的作用机制研究,2023.1-2025.12,10.00万元,在研,主持。
教学情况
主讲本科药理学课程。
论文、专著及专利等
在学术刊物上发表科研论文30余篇。代表作:
第一作者
1. Hongjin Chen, et al. Centromere protein F is identified as a novel therapeutic target by genomics profile and contributing to the progression of pancreatic cancer, Genomics. 2020 Nov 6;S0888-7543(20)32003-6. doi: 10.1016/j.ygeno.2020.10.039.(SCI,二区,IF=6.205,第一作者)
2. Hongjin Chen, et al. Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury. Phytomedicine, 2019, 63:152997(SCI,一区,IF=4.268,第一作者)
3. Hong-Jin Chen, et al. Understanding the inflammation-cancer transformation in the development of primary liver cancer, Hepatoma Research, 2018;4:29. DOI: 10.20517/2394-5079.2018.18.(综述,非SCI,第一作者)
4. Hongjin Chen, et al. Inhibition of high glucose-induced inflammation and fibrosis by a novel curcumin derivative prevents renal and heart injury in diabetic mice. Toxicology Letters, 2017, 278:48-58.(SCI,二区,IF=3.596,第一作者)
5:Hongjin Chen, et al. Overexpression of RhoV promotes the progression and EGFR-TKI resistance of lung adenocarcinoma, Frontiers in Oncology, 2021 Mar 9:11:619013. .(SCI,二区,IF=4.848,第一作者)
6:Hongjin Chen, et al. Centromere protein F promotes progression of hepatocellular carcinoma through ERK and cell cycle-associated pathways, Cancer Gene Therapy, 2022 Jul;29(7):1033-1042. ( SCI,二区,IF=4.534,第一作者)
7:Hongjin Chen, et al. Curcumin Derivative C66 Suppresses Pancreatic Cancer Progression through the Inhibition of JNK-Mediated Inflammation, Molecules, 2022 May 11;27(10):3076. ( SCI,二区,IF=4.2,第一作者)
8:Hongjin Chen, et al. Acute or chronic inflammation role in gastrointestinal oncology, World J Gastrointest Oncol. 2022 Aug 15;14(8):1600-1603. (SCI,三区,IF=2.5,第一作者)
9:Hongjin Chen, et al. Multifunctional roles of inflammation and its causative factors in primary liver cancer: A literature review. World J Hepatol .2023 Dec 27;15(12):1258-1271.( IF=2.5,第一作者)
10: Hongjin Chen, et al. Effects of vitamin family members on insulin resistance and diabetes complications. World J Diabetes. 2024 Mar 15;15(3):568-571. (SCI, Q1,IF=4.2,第一作者)
通讯作者
1. Yi Zhang# , Hui Liu# , Wenjing Jia# , Jiayu Qi, Wentao Zhang, Wenxin Zhang, Guang Liang, Yali Zhang, Hongjin Chen*. Myeloid differentiation protein 2 mediates angiotensin II induced liver inflammation and fibrosis in mice. Molecules, 2020, 25(1), 25.(SCI,三区,IF=3.267,通讯作者)
2. Jue Bai#, Si-Yuan Yang#, Shao-Mei Yu, Ying Cao, Xuan-Yi Hu, Xiong Chen, Ying-Nan Song*, Hong-Jin Chen*, IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance, Frontier in Pharmacology, 2025, accept. (SCI,二区,通讯作者)
并列第一作者(6篇)
1. Xiaozhong Huang, et al, Cell Death Dis. 2020 Dec 7;11(12):1040. doi: 10.1038/s41419-020-03260-9.(SCI,二区,IF=6.3,共一/自然序列:第三作者)
2. Yali Zhang, et al, BBA - Molecular Basis of Disease, 2020 Jan 14;1866(5):165683.(SCI,二区,IF=4.8,共一/自然序列:第二作者)
3. Chunyong Ding, et al, Chemical Science, 2019, 10:4667-4672.(SCI,一区,IF=9.34,共一/自然序列:第二作者)
4. Lingfeng Chen, et al. European Journal of Medicinal Chemistry, 2019: 161, 22-38.(SCI,一区,IF=5.573,共一/自然序列:第二作者)5. Dandan Liang, et al. BBA - Molecular Basis of Disease, 2018, 1864(1): 133-142.(SCI,二区,IF=4.8,共一/自然序列:第二作者)6. Lingfeng Chen, et al. Eur. J Med. Chem, 2017, 143: 361-375.(SCI,一区,IF=5.573,共一/自然序列:第三作者)
共同作者(13篇)
1. Yang SiYuan, et al. Adv Healthc Mater,2023 Sep;12(23):e2300410.(SCI,第四作者)
2. Liu Zhou, et al, Frontier in Pharmacology, 2024 Nov 13:15:1476718.(SCI,第二作者)
3. Xu, Tengfei, et al, Environmental Science & Technology, 2021 Jan 18.(SCI,第五作者)
4. Mei Wang, et al, Neurotherapeutics. 2020 Aug 21.(SCI,第四作者)
5. Chao Hu, et al, Clinical and Translational Medicine, 2020 Jun 14. (SCI,第四作者)
6. Tingting Xu et al, Aging (Albany NY). 2019 Nov 6; 11. (SCI,第五作者)
7. Wenxin Zhang et al, Molecular Medicine Reports, 2019 Jun; 19(6): 4770–4778. (SCI,第二作者)
8. Wubeibei Wu et al, Biomedicine & Pharmacotherapy, 2019 Feb;110:951-960. (SCI,第四作者)
9. Yali Zhang et al. British Journal of Pharmacology, 2018, 175(5): 840-854. (SCI,第七作者)
10. Yali Zhang et al, Eur. J Med. Chem, 2018, 148: 291-305.(SCI,第五作者)
11. Siyang Xiao et al. Drug Design, Development and Therapy, 2018, 12: 887-899. (SCI,第三作者)
12. Yali Zhang et al, Journal of Cellular and Molecular Medicine, 2017, 21(4): 746-757.(SCI,第四作者)
Xiangting Ge et al, Drug Design, Development and Therapy, 2016, 10: 1947–1959. (SCI,第五作者)